Rachael Baker

Rachael Baker


  • B.S., Calvin College, 2008
  • Ph.D., Biochemistry and Biophysics, University of North Carolina at Chapel Hill, 2013

Professional experience

  • Assistant Professor of Chemistry, Calvin College, 2014-present
  • Postdoctoral Fellow, UNC Chapel Hill, 2013-2014

Academic interests

  • Rare Diseases
  • Mitochondrial Structure and Function
  • Post translational modifications
  • Using traditions from Christian community to inform collaborative research practices

Research and scholarship


Rachael A. Baker, Jessica R.C. Priestley, Amy M. Wilstermann, Kalina J. Reese, Paul R. Mark (2018) Clinical Spectrum of BCS1L Mitopathies and their Underlying Structural Relationships. American Journal of Medical Genetics Part A. 1-8.

Mason Swartz, Philip Tubergen, Chad Tatko, and Rachael A. Baker (2018) Experimental Determination of pKa values and Metal Binding for Biomolecular Compounds Using 31P NMR Spectroscopy. Journal of Chemical Education. 95 (1), 182-185.

Gauri Dixit*, Rachael Baker*, Carly M. Sacks, Matthew Torres, and Henrik G. Dohlman (2014) Guanine Nucleotide-Binding Protein (Gα) Endocytosis by a Cascade of Ubiquitin Binding Domain Proteins is Required for Sustained Morphogenesis and Proper Mating in Yeast. Journal of Biological Chemistry. 289 (21): 15052-15063.
*These authors contributed equally to this work

Rachael Baker, Emily M. Wilkerson, Kazutaka Sumita, Daniel G. Isom, Atsuo Sasaki, Henrik G. Dohlman, and Sharon L. Campbell (2013) Differences in the Regulation of K-Ras and H-Ras Isoforms by Monoubiquitination. Journal of Biological Chemistry. 288 (52): 36856-36862.

Daniel G. Isom, Vish Sridharan, Rachael Baker, Sarah T. Clement, David M. Smalley, and Henrik G. Dohlman (2013) Protons as Second Messenger Regulators of G Protein Signaling. Molecular Cell. 51 (4): 531-538.

Rachael Baker, Steven M. Lewis, Emily M. Wilkerson, Atsuo T. Sasaki, Lewis C. Cantley, Brian Kuhlman, Henrik G. Dohlman, and Sharon L. Campbell (2013) Site-Specific Monoubiquitination Activates Ras by Impeding GTPase Activating Protein Function.  Nature Structural and Molecular Biology.  20 (1): 46-52.
Highlighted in Nature Reviews Molecular and Cell Biology: Katharine Wrighton (2013) Cell Signaling: How Monoubiquitination Keeps RAS Active. 14, 66-67.

Steven D. Cappell, Rachael Baker, Dorota Skowyra, and Henrik G. Dohlman (2010) Systematic Analysis of Essential Genes Reveals Important Regulators of G Protein Signaling. Molecular Cell38 (5): 746–757.

Kristin M. Slade, Rachael Baker, Michael Chua, Nancy L. Thompson, and Gary J. Pielak (2009) Effects of Recombinant Protein Expression on Green Fluorescent Protein Diffusion in Escherichia coli. Biochemistry.  48 (23): 5083-5089.


2018 Kelsey Wright Award for Excellence in Mitochondrial Medicine

In the news

Show your stripes at Calvin University's Rare Disease Symposium

Calvin University Rare Disease Research & Support will host a Rare Disease Symposium on Rare Disease Day, February 29th, 2020 at the Prince Conference Center.

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