Larry Louters

Larry Louters


  • B.A. Dordt College, 1971
  • M.S., Organic Chemistry, University of Minnesota, 1974
  • Ph.D. Biochemistry, University of Iowa, 1984

Thesis: Exchange of Nucleosomal Histones
Advisor: Dr. Roger Chalkley

Professional experience

  • 1984-present: Professor of Chemistry, Calvin University (College); Chair of the Department (2008-2010, 2010-2012)
  • 1990-1991: Visiting Professor at University of Arizona
  • 1973-1979: Chemistry/Biology Teacher, Dept. Chairman, Coach, Evangelical Christian School, Memphis, TN


Weekly Schedule
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2012 Presidential Award
Professor Louters received Calvin's highest accolade: 2012 Presidential Award for Exemplary Teacher


Undergraduate student names appear in bold

Miranda F. Bouwer, Kathryn E. Hamilton, Patrick B. Jonker, Sam R. Kuiper, Larry L. Louters, Brendan D. Looyenga. "NMS-873 functions as a dual inhibitor of mitochondrial oxidative phosphorylation", Biochimie 185. Pages 33-42, 2021

Lodge EK, Bell JD, Roloff EM, Hamilton KE, Louters LL, Looyenga BD. "Pharmacologic inhibition of N-linked glycan trimming with kifunensine disrupts GLUT1 trafficking and glucose uptake". Biochimie. pii: S0300-9084(20)30071-7. [Epub]. PMID: 32298759 13 April 2020

Rylaarsdam LE, Johnecheck GN, Looyenga BD, Louters LL. 2019. "GLUT1 is Associated with Sphingolipid-Organized, Cholesterol-Independent Domains in L929 Mouse Fibroblast Cells". 162:88-96. PMID: 30980844, Jul 2019.

Hamilton KE, Rekman JF, Gunnink LK, Busscher BM, Scott JL, Tidball, AM, Stehouwer NR, Johnecheck GN, Looyenga BD, Louters LL. Quercetin Inhibits Glucose Transport by Binding to an Exofacial Site on GLUT1, Biochimie 151, 107-114. 2018.

Gunnink LK, Busscher BM, Wodarek JA, Rosette KA, Strohbehn LE, Looyenga BD, Louters LL, Caffeine Inhibition of GLUT1 is Dependent on the Activation State of the Transporter, Biochimie 137, 99-105. 2017.

Looyenga, B., Van Opstall, Z. Lee, J. Bell, E. Lodge, K. Wrobel, E. Arnoys, and L. Louters. Determination of GLUT1 Oligomerization Parameters Using Bioluminescent Förster Resonance Energy Transfer. Science Reports. 6:1-14. 2016.

Gunnink LK, Alabi OD, Kuiper BD, Gunnink SM, Schuiteman SJ, Strohbehn LE, Hamilton KE, Wrobel KE, Louters LL, Curcumin Directly Inhibits the Transport Activity of GLUT1, Biochimie 125, 179-185. 2016

Alabi OD, Gunnink SM, Kerk SA, Braun E, Louters LL, Osthole Activates Glucose Uptake But Blocks Full Activation in L929 Fibroblast Cells, and Inhibits Uptake in HCLE Cells, Life Sciences 102, 105-110. 2014

Gunnink SM, Kerk SA, Kuiper BD, Alabi OD, Kuipers DP, Praamsma RC, Wrobel KE, Louters LL, Alkaline pH Activates the Transport Activity of GLUT1 in L929 Fibroblast Cells, Biochimie 99, 189-194. 2014

Kuipers DP, Scripture JP, Gunnink SM, Salie MJ, Scotanus MP, Ubels JL, Louters LL. Differential Regulatin of GLUT1 Activity in Human Corneal Limbal Epithelial Cells and Fibroblasts, Biochimie 95, 258-263. 2013. 

Louters LL, Scripture JP, Kuipers DP, Gunnink SM, Kuiper BD, Alabi OD, Hydroxlylamine Acutely Activates Glucose Uptake in L929 Fibroblast Cells, Biochimie 95, 787-792. 2013.

Salie MJ, Oram DS, Kuipers DP, Scripture JP, Chenge J, MacDonald GJ, Louters LL. Nitroxyl (HNO) Acutely Activates the Glucose Uptake Activity of GLUT1, Biochimie 94, 864-869. 2012.

Cok A, Plaisier C, Salie MJ, Oram DS, Chenge J, Louters LL. Berberine Acutely Activates the Glucose Transport Activity of GLUT1, Biochimie 93, 1187-1192. 2011. 

Plaisier C., Cok A., Scott J., Opejin A., Bushhouse K.T., Salie M.J., Louters L.L. Effects of cinnamaldehyde on the glucose transport activity of GLUT1, Biochimie 93, 339-344. 2011. 

Louters L.L., Stehouwer N., Rekman J., Tidball A., Cok A., Holstege C.P. Verapamil inhibits the glucose transport activity of GLUT1, J Med Toxicicology 6, 100-5. 2010.

"Methyl-β-cyclodextrin Directly Binds Methylene Blue and Blocks Both its Cell Staining and Glucose Uptake Stimulatory Effects," Scott, J.; Uitvlugt, J. M.; Tidball, A.; Lucia, M.; Vander Griend, D. A.; Louters, L. L. Biochemie, 91, 271-276. 2009

Scott J., Opejin A., Tidball A., Stehouwer N., Rekman J., Louters L.L. Dual action of phenylarsine oxide on the glucose transport activity of GLUT1, Chemico-Biol Interactions 182, 199-203. 2009. 

Louters L.L., Stehouwer N., Rekman J., Tidball A., Cok A., Holstege C.P. Verapamil inhibits the glucose transport activity of GLUT1, Clinical Toxicology 47, 2009; Abs 155.

Roelofs B., Tidball A., Lindborg A.E., Ten Harmsel A., Vander Kooy T.O., and Louters L.L. Acute activation of glucose uptake by glucose deprivation in L929 fibroblast cells.  Biochemie 88, 1941-1946. 2006.

Louters L.L., Dyste S.G., Frieswyk D., TenHarmsel A., Vander Kooy T.O., Walters L., and Whalen T. Methylene blue stimulates 2-deoxyglucose uptake in L929 fibroblast cells. Life Sciences 78, 586-591. 2006.

TenHarmsel A., Holstege C.P., Louters L.L. High dose insulin reverses verapamil 
inhibition of glucose uptake in mouse striated muscle. Ann Emerg Med 46(3), S77. 2005.

Van Dyke D.A., Walters  L., Freiswyk D., Kokemeyer D., and Louters L.L. Acute effects of troglitazone and nitric oxide on glucose uptake in L929 fibroblast cells, Life Sciences 72, 2003; 2321-2327.

Vander Lugt J.T., Gomez-Marquez J., Caldon J., and Louters L.L. Combined effects of troglitazone and muscle contraction on insulin sensitization in Bulb-c mouse muscle, Biochemie, 83, 2001; 445-451.


2012 Presidential Award - Prof. Louters received Calvin's highest accolade, the 2012 Presidential Award for Exemplary Teaching.

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