Douglas A. Vander Griend

Douglas Vander Griend


  • B.A. Calvin College, Chemistry, 1996
  • Ph.D. Northwestern University, Inorganic Chemistry, 2000


Professor Vander Griend's News & Stories' faculty profile (July 26, 2010)

Professional experience

  • Calvin College, 2002-present, Professor of Chemistry
  • Furman University, 2000-2002, Dreyfus Postdoctoral Fellow

Academic interests

  • Synthetic nanotechnology
  • Inorganic thermochromic materials
  • Chemometric analysis of spectroscopic data

Research and scholarship


43) “Properly Handling Negative Values in the Calculation of Binding Constants by Physicochemical Modeling of Spectroscopic Titration Data” Kazmierczak, N.; Vander Griend, D. A. J. Chemometrics 2019, under review.

42) “Sensitivity Limits for Determining 1:1 Binding Constants from Spectrophotometric Titrations via Global Analysis” Kazmierczak, N.; Chew, J. A.; Michmerhuizen, A. R.; Kim, S. E.; Drees, Z. D.; Rylaarsdam, A.; Thong, T.; Van Laar, L.; Vander Griend, D. A. J. Chemometrics, 2019, 33, 1-13.

41) “Radius Ratio Rule Rescue” Michmerhuizen, A.; Rose, K.; Annankra, W.; Vander Griend, D. A. J. Chem. Educ. 2017, 94, 1480-1485.

40) “Fricke-Gel Dosimeter: Overview of Xylenol Orange Chemical Behavior” Liosi, G. M.; Dondi, D.; Vander Griend, D.; Lazzaroni, S.; D’Agostino, G.; Mariani, M. Radiation Physics and Chemistry 2017, 140, 74–77.

39) “Improving Student Results in the Crystal Violet Chemical Kinetics Experiment” Kazmierczak, N.; Vander Griend, D. A. J. Chem. Educ. 2017, 94, 61-66.

38) “A Chiroptical Molecular Sensor for Ferrocene” Agnes, M.; Nitti, A.; Vander Griend, D. A.; Dondi, D.; Merli, D.; Pasini, D. Chem. Commun. 2016, 52 (77), 11492–11495.

37) “The crystal structure of a valinomycin·2Ca2+ complex and the multi-step solution equilibria in acetonitrile characterized by 1H NMR, UV-Vis, and mass spectrometry” Contractor, A. A.; Kazerouni, A. M.; Michmerhuizen, A. R.; Falkenberry, M. L.; Segovia, R.; Blair, N. M.; Kim, S.; Vander Griend, D. A.; Bacsa, J.; Khan, F. A.; Fujita, M., Supramolecular Chemistry, 2016, 29, 129-138.

36) “Functional characterization of a cadmium resistance operon in Staphylococcus aureus ATCC12600: CadC does not function as a repressor” Hoogewerf, A. J.; Van Dyk, L. A.; Buit, T. S.; Roukema, D.; Resseguie, E.; Plaisier, C. L.; Le, N.; Heeringa, L. Vander Griend, D. A., J. Basic Microbiol., 2015, 55, 148-59.

35) “Self-Assembly Snapshots of a 2×2 Copper(I) Grid” Manck, L. E.; Benson, C. R.; Share, A. I. Park, H.; Vander Griend, D. A.; and Flood, A. H., Supramolecular Chemistry, 2014, 26, 267-279.

34) "Reaction Extrema" Vandezande, J. E.; Vander Griend, D. A.; DeKock, R.L., J. Chem. Ed., 2013, 90, 1177-1179.

33) "A Chiroptical Probe for Sensing Metal Ions in Water" Caricato, M.; Jordana Leza, N.: Roy, K.; Dondi, D.; Gattuso, G.; Shimizu, L. S.; Vander Griend, D. A.; Forni, A.; and Pasini, D. Eur. J. Org. Chem., 2013, 27, 6078-6083.

32) "From Red to Blue Shift: Switching the Binding Affinity from the Acceptor to the Donor End by Increasing the π-Bridge in Push-Pull Chromophores with Coordinative Ends" Caricato, M.; Coluccini, C.; Vander Griend, D. A.; Forni, A.; and Pasini, D. New J. Chem., 2013, 37, 2792-2799.

31) “Modeling Methylene Blue Aggregation in Acidic Solution to the Limits of Factor Analysis” Golz, E. M.; Vander Griend, D. A., Anal. Chem., 2013, 85, 1240-1246.

30) "Detailed Spectroscopic and Thermodynamic Characterization of Nickel(II) Complexes with Methyl/pyridine attained via Factor Analysis" Bediako, D. K.; Vander Griend, D. A., J. Undergraduate Chem. Res., 2013, 12(1), 11-15.

29) "Equilibrator: Modeling Chemical Equilibria with Excel" Vander Griend, D.A., J. Chem. Ed., 2011, 88, 1727-1729. pdf.

28) "Spectroscopic and electrochemical sensing of Lanthanides with pi-extended chromophores incorporating ferrocenes and a coordinative end." Coluccini, C.; Sharma, A.K.; Merli, D.; Vander Griend, D.A.; Mannucci, B.; Pasini, D., Dalton Trans., 2011, 40, 11719-11725. pdf.

27) "Structures, host–guest chemistry and mechanism of stepwise self-assembly of M4L6 tetrahedral cage complexes" Benjamin R. Hall, Lauren E. Manck, Ian S. Tidmarsh, Andrew Stephenson, Brian F. Taylor, Emma J. Blaikie, Douglas A. Vander Griend and Michael D. Ward Dalton Trans., 2011, 40, 12132-12145. pdf.

26) "Bond Order and Chemical Properties of BF, CO, and N2." Martinie, R. J.; Bultema, J.J.; Vander Wal, M. N.; Burkhart, B.J.; Vander Griend, D.A.; DeKock, R.L., J. Chem. Ed., 2011, 88, 1094-1097. pdf.

25) "Nesting Complexation of C60 with Large, D2 symmetrical Molecules." Coluccini, C.; Dondi, D.; Vander Griend, D.A.; Pasini, D.; Caricato, M. Org. Biomol. Chem., 2010, 8, 3272-3280. pdf.

24) "Dynamic Switching between Binding Sites in the Complexation of Macrocyclic 'Push-Pull' Chromophores to Lanthanides." Coluccini, C.; Pasini, D.; Righetti, P. Vander Griend, D.A., Tetrahedron, 2009, 65, 10436-10440. pdf.

23) "Reduction of a redox-active ligand drives switching in a Cu(I) psuedorotaxane by a bimolecular mechanism." McNitt, K.; Parimal, K.; Share, A.; Fahrenbach, A.; Witlicki, E.; Pink, M.; Bediako, D.; Plaisier, C.; Le, N.; Heeringa, L.; Vander Griend, D.A.; Flood, A. J. Am. Chem. Soc. 2009, 131, 1305-1313. pdf.

22) "Methyl-β-cyclodextrin directly binds methylene blue and blocks both its cell staining and glucose uptake stimulatory effects," Scott, J.; Uitvlugt, J. M.; Tidball, A.; Lucia, M.; Vander Griend, D. A. ; Louters, L. L. Biochemie, 2009, 91, 271-276. pdf.

21) "Modeling triazolophane-halide binding equilibria using Sivvu analysis of UV-Vis titration data recorded under medium binding conditions," Flood, A. H. ; Li, Y.; Vander Griend, D. A. Supramolecular Chemistry, 2009, 21, 111-117, pdf.

20) "Detailed Spectroscopic, Thermodynamic and Kinetic Characterization of Nickel(II) Complexes with 2,2'-bipyridine and 1,10-phenanthroline attained via Equilibrium-Restricted Factor Analysis," Bediako, D.K.; DeVries, M.J.; DeJong, N.A.; Heeringa, L.P.; Vander Griend, D.A. Inorg. Chem. 2008,47, 656-662. pdf.

19) "Equilibrium: A Teaching/Learning Activity," Vander Griend, D.A. J. Chem. Ed. 2007, 84, 1428. pdf.

18) Sivvu (Computer Program for Unrestricted and Equilibrium-Restricted Factor Analysis of Spectrophotometric Data), DeVries, M. J.; Vander Griend, D. A. 2006.

17) "Chemistry and Materials Science for All Engineering Disciplines: A Novel Interdisciplinary Team-Teaching Approach," VanAntwerp, J. J. VanAntwerp, J. G.; Vander Griend, D. A.; Wentzheimer, W. W. Am. Soc. Engr. Educ. 2004, 1171.


1) Ligand exchange thermochromic systems and high ε ligands , US 8,431,045, 2013.

2) Ligand exchange thermochromic systems and high ε ligands , US 8,182,718, 2012.

3) Ligand exchange thermochromic, (LETC), systems, US 8,018,639, 2011.

4) Ligand exchange thermochromic (LETC) systems, US 7,542,196, 2009.

5) Ligand exchange thermochromic systems containing exchange metals, US 7,538,931, 2009.

6) Multi-Layer ligand exchange thermochromic systems. US 7,525,717, 2009.

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