HIV as a Latent Reservoir in Resting T Helper Cells
- Dates: 2006–2011
- Faculty researcher(s):
Ongoing research investigating how HIV remains as a latent reservoir in resting T helper cells to ensure viral persistence in patients that have undergone treatment with highly active antiretroviral therapy (HAART).
Currently, HIV latency is the most significant problem preventing a cure for AIDS. In this study, a replication incompetent pseudotyped virus system is used to investigate how endothelial cells interact with resting T helper cells to promote HIV infection and latency formation.
Student Contributors: Tran Nguyen, Abuoma Nwadike, Wei Wang, John Morris, Anne Barron, John Morris, Yelena Boykov, Jake Baker, Geoff Scott
- Course code: