HIV as a Latent Reservoir in Resting T Helper Cells

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  • Dates: 2006–2011
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Ongoing research investigating how HIV remains as a latent reservoir in resting T helper cells to ensure viral persistence in patients that have undergone treatment with highly active antiretroviral therapy (HAART).

Currently, HIV latency is the most significant problem preventing a cure for AIDS. In this study, a replication incompetent pseudotyped virus system is used to investigate how endothelial cells interact with resting T helper cells to promote HIV infection and latency formation.

Student Contributors: Tran Nguyen, Abuoma Nwadike, Wei Wang, John Morris, Anne Barron, John Morris, Yelena Boykov, Jake Baker, Geoff Scott


Anding Shen

Anding Shen

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